Farming Difficulty

Nidus Prime
Prime Warframe Farming Guide with relic source coverage, drop rates, and farming strategy.
Relics Tracker
Relics in DB: 26 relics tracked
Mutation is endless. The ravening plague-bearer returns in a long-unseen form, seething with a primal strain of the Infestation.
Nidus Prime is currently vaulted. It moved into the vault on July 27, 2023. You can still acquire relics through player trading and Prime Resurgence windows, then run coordinated Radiant shares for better rare-part odds.
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Nidus Prime Drop Rate Summary
Visual summary of where this Prime item is sourced by relic tier and how its part drops are split between Common, Uncommon, and Rare pools.
Relic Tier Availability
Drop Pool Rarity Mix
Systems Blueprint
Blueprint
Chassis Blueprint, Neuroptics Blueprint
Prime Access Bundle
Nidus Prime was released with these Signature Prime items:
Nidus Prime Farming Overview and Stats
Warframe Abilities
Virulence
Rupture the ground with a damaging fungal growth that steals energy from each enemy it strikes. For every five enemies hit, the Infestation mutates, multiplying its destructive force.
Larva
Spawn an Infested pod that erupts with tendrils, latches onto nearby enemies and pulls them in. Enemies killed while held have a chance of generating a Mutation stack.
Parasitic Link
Bind to a target with parasitic link. When cast on an ally, both the host and Nidus have their Ability Strength increased. Linked enemies take some of the damage inflicted on Nidus.
Ravenous
Gluttonous maggots swarm nearby enemies, feasting until they are hit with Virulence and burst with Infestation. The maggots benefit from Mutation and each enemy hit adds to the Mutation stack.
Nidus Prime vs Nidus
| Stat | Nidus | Nidus Prime | Difference |
|---|---|---|---|
| Health | 455 | 550 | +95 |
| Shield | 0 | 0 | - |
| Armor | 350 | 425 | +75 |
| Energy | 100 | 140 | +40 |
The Primed variants offer improved stats over the base versions, and most importantly better armor which is what we call truly end-game.
How To Craft Nidus Prime

Credits Cost
25,000
Build Time
3 days

Rush Cost
50 Platinum
Required Components

Blueprint

Chassis

Neuroptics

Orokin Cell

Systems
How To Farm Nidus Prime Relics
Track Your Relics
Click each checkbox for relics you already own, then review your collection in Relic Tracker. Selections are saved locally on this device.
Blueprint
8 Source RelicsChassis Blueprint
6 Source RelicsNeuroptics Blueprint
4 Source RelicsNidus Prime Farming Strategy and Radshare Tips
Optimal Approach:
- Go for the Neuroptics Blueprint first. It has the lowest item drop rate in the Nidus Prime set and will be the hardest to farm, when comparing to other parts.
- Best relic to focus: Neo N16 (currently vaulted - trade with a player for the relic or wait for Prime Resurgence access).
- In full radiant relic squad, you have a 34.39% chance per run vs 10.00% when running solo.
- After that: Chassis Blueprint from Lith N12 (10.00% per-player for Radiant).
Refinement Tips:
- Use Radiant (100 Traces) on Neo N16 while going for the Neuroptics Blueprint; always run radshares in groups.
- At current rates, you can expect roughly 2 Radshare runs for 50% odds for the required prime part, compared with about 7 solo runs.
- Run Intact/Exceptional Relics only when farming for common or uncommon primes (these are great for ducat farming), use Void Traces for the relics with hard to farm parts. Especially Axi Relics.
About the Author
Vikas Bhatt
Warframe veteran with 4,000+ hours of gameplay, playing since the "Void Keys" era. With over ten years of editorial experience, he specializes in relic farming optimization and Prime acquisition strategies. Vikas's articles have been featured on multiple gaming outlets like IGN, Gamespot, Kotaku to name a few. He is also the founder of Warframe Relics.







