
Prime Warframe Farming Guide
Mutation is endless. The ravening plague-bearer returns in a long-unseen form, seething with a primal strain of the Infestation.

"Market forces dictate that you need to evolve or die."
Nidus Prime is Vaulted. Players looking to obtain it have to trade with other players for the relics or the parts. For more efficient runs, you can purchase the rare relics and run a radiant group.
Nidus Prime was released with these Signature Prime items:
Rupture the ground with a damaging fungal growth that steals energy from each enemy it strikes. For every five enemies hit, the Infestation mutates, multiplying its destructive force.
Spawn an Infested pod that erupts with tendrils, latches onto nearby enemies and pulls them in. Enemies killed while held have a chance of generating a Mutation stack.
Bind to a target with parasitic link. When cast on an ally, both the host and Nidus have their Ability Strength increased. Linked enemies take some of the damage inflicted on Nidus.
Gluttonous maggots swarm nearby enemies, feasting until they are hit with Virulence and burst with Infestation. The maggots benefit from Mutation and each enemy hit adds to the Mutation stack.
| Stat | Nidus | Nidus Prime | Difference |
|---|---|---|---|
| Health | 455 | 550 | +95 |
| Shield | 0 | 0 | - |
| Armor | 350 | 425 | +75 |
| Energy | 100 | 140 | +40 |
The Primed variants offer improved stats over the base versions, and most importantly better armor which is what we call truly end-game.

Credits Cost
25,000
Build Time
3 days

Rush Cost
50 Platinum

Blueprint

Chassis

Neuroptics

Orokin Cell

Systems
Track Your Relics
Click each checkbox for relics you already own, then review your collection in My Relics. Selections are saved locally on this device.
About the Author
Warframe veteran with 4,000+ hours of gameplay, playing since the "Void Keys" era. With over ten years of editorial experience, he specializes in relic farming optimization and Prime acquisition strategies. Vikas's articles have been featured on multiple gaming outlets like IGN, Gamespot, Kotaku to name a few. He is also the founder of Warframe Relics.